Quatrefolic® vs Folic Acid

Several studies have reported an increase in serum and unmetabolized folic acid (UMFA) levels since the implementation of folic acid fortification, with possible concern about its potential adverse effect.

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EFSA health claim on folates

The use of supplemental folate reduces the risk of neural tube defects.




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Positive List amendment

Following the Authority's favorable opinion the list of vitamin and mineral substances, set out in Annex II to Directive 2002/46/EC, has been officially amended to include Quatrefolic®, the glucosamine salt...

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